Ketoconazole or Nizoral

Ketoconazole is cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxyl]phenyl] piperazine.

Ketoconazole is a white to slightly beige, odorless powder, soluble in acids, with a molecular weight of 531.44.  It is an antifungal agent, quite effective.

Tablets: Ketoconazole is a synthetic broad-spectrum antifungal agent available in scored white tablets, each containing 200 mg ketoconazole base for oral administration. Inactive ingredients are colloidal silicon dioxide, corn starch, lactose, magnesium stearate, microcrystalline cellulose, and povidone.

Shampoo: Ketoconazole 2% Shampoo is a red-orange liquid for topical application, containing the broad-spectrum synthetic antifungal agent ketoconazole in a concentration of 2% in an aqueous suspension. It also contains: coconut fatty acid diethanolamide, disodium monolauryl ether sulfosuccinate, FD&C Red No. 40, hydrochloric acid, imidurea, laurdimonium hydrolyzed animal collagen, macrogol 120 methyl glucose dioleate, perfume bouquet, sodium chloride, sodium hydroxide, sodium lauryl ether sulphate, and purified water.

Cream: Ketoconazole 2% cream contains the broad-spectrum synthetic antifungal agent ketoconazole 2% formulated in an aqueous cream vehicle consisting of propylene glycol, stearyl and cetyl alcohols, sorbitan monostearate, polysorbate 60, isopropyl myristate, sodium sulfite anhydrous, polysorbate 80 and purified water.

CATEGORIES, BRAND NAMES

CATEGORIES: Blastomycosis; Candidiasis; Coccidioidomycosis; Histoplasmosis; Infection, Fungal; Infection, Skin; Tinea Corporis; Tinea Cruris; Tinea Pedis; Tinea Versicolor; Pregnancy Category C; FDA Approved 1981 Jun; WHO Formulary

FDA Drug Class: Antifungals; Dermatologics; Topical Anti-Infectives

BRAND NAMES: Akorazol; Anfuhex; Aquarius; Conazol; Formyco; Funazole; Funazole Tabs; Fungarest; Fungazol; Fungazol Tabs; Fungicide; Fungicide Tabs; Funginox; Funginox Tabs; Fungoral; Kenazol; Ketoconazol; Ketoderm; Ketoisdin; Ketomicon; Ketozol; Mycofebrin; Nazoltec; Niz Creme; Niz Shampoo; Nizoral; Nizoral 2% Cream; Nizoral Cream and Tablets; Nizoral Shampoo; Nizoral Tablets; Nizoral Tabs and Cream; Panfungol; Pasalen; Spike; Sporozol; Termizol; Unidox; Zoralin; Zoralin Tabs
(Foreign brand names outside U.S. in italics)

COST OF THERAPY: $21.47 (Candidiasis; Tablet; 200 mg; 1/day; 7 days)

[Return to associated illnesses with fungal exposure page]